Most UPS recur locally; distant metastases are common (the most frequent is lung) atypical fibroxanthoma or dermatofibrosarcoma protuberans (see this term).

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TB often pre- sents an atypical behaviour, which may pose difficulties to the diagnosis9. In countries with high incidence of TB, cases caused by new infection 

2011-11-01 · Atypical fibroxanthoma (AFX) and malignant fibrous histiocytoma (MFH) belong to a group of fibrohistiocytic tumours that are considered to have a variable aggressiveness. 1 In 1961, Helwig first coined the term ‘atypical fibroxanthoma’ to describe an atypical dermal spindle-cell tumour that exhibited a benign course. 1 AFX is thought to be related to actinic damage and ultraviolet (UV Ang GC, Roenigk RK, Otlev CC, Kim Phillips P, Weaver AL. More than 2 decades of treating atypical fibroxanthoma at mayo clinic: what have we learned from 91 patients? Dermatol Surg. 2009; 35(5):765-72. Kargi E, Gungor E, Verdi M, Kuiaçogiu S, Erdogan B, Alli N, et al. Atypical fibroxanthoma and metastasis to the lung.

Atypical fibroxanthoma metastasis

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Atypical Fibroxanthoma on the Ear Atypical fibroxanthoma is a low-grade sarcoma of the skin. (See also —is done if clinically appropriate. Metastasis is unusual. Prevention Because atypical fibroxanthomas seem to be related to ultraviolet (UV) exposure, a number of measures are recommended to … Atypical fibroxanthoma lesions occasionally extend to the subcutaneous tissue. Note that atypical fibroxanthoma is a dermal-based process while spindle cell squamous cell carcinoma variants (on the differential diagnosis) connect with the epidermis and show signs of keratinization. DOI: 10.1097/00006534-200304150-00032 Corpus ID: 26453610.

2017 Aug 17. [Medline] .

What are the clinical features of atypical fibroxanthoma? A solitary tumour or multiple tumours may occur. Typically, AFX is a red, juicy, dome-shaped nodule that may be bleeding, ulcerated or crusted. The tumour starts off as a small nodule that grows quickly over 6 months to a size of about 2–3

BACKGROUND: Atypical fibroxanthoma (AFX) is a low-grade sarcoma usually occurring on sun-damaged skin of the head and neck in elderly patients. Metastatic disease has been reported very rarely. The potential aggressiveness of AFX is controversial.

Atypical fibroxanthoma metastasis

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The vast majority of AFX behave in a benign manner, and metastasis is rare. Eight examples of metastasizing AFX are reported. Factors that portend agressive behavior and metastasis are vascular invasion, recurrence, deep tissue invasion Metastatic atypical fibroxanthoma of skin Metastatic atypical fibroxanthoma of skin Jacobs, David S.; Edwards, William D.; Ye, Richard C. 1975-02-01 00:00:00 A case is presented of postirradiation atypical fibroxanthoma of the skin, metastatic to cervical lymph node, in a young female. CONCLUSION: Metastases attributed to atypical fibroxanthoma are rare, and many prior reports may have actually been malignant fibrous histiocytoma, spindle cell melanoma, or spindle cell squamous carcinoma. Tumor depth, vascular invasion, and cutaneous tumor recurrence appear to increase risk for metastasis. Atypical fibroxanthoma with regional lymph node metastasis: report of a case and review of the literature.

Prevention Because atypical fibroxanthomas seem to be related to ultraviolet (UV) exposure, a number of measures are recommended to … Atypical fibroxanthoma lesions occasionally extend to the subcutaneous tissue. Note that atypical fibroxanthoma is a dermal-based process while spindle cell squamous cell carcinoma variants (on the differential diagnosis) connect with the epidermis and show signs of keratinization.
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Atypical fibroxanthoma metastasis

Atypical fibroxanthoma tumor-like growth should be considered a type of skin cancer but it may behave in a benign fashion.

OBJECTIVE: We report a case of localized cutaneous metastases attributed to an atypical fibroxanthoma. METHODS: A case report and a review of the literature of metastasizing atypical fibroxanthoma are given. 1986-02-01 Atypical fibroxanthoma of the scalp with recurrent and multiple regional cutaneous metastases Jennifer Nergard, BS, Julie Glener, BS, Danielle Reimer, BS, within a short period.3,4 The risk of metastasis is increased by tumor depth, vascular invasion, and cutaneous tumor recurrence.4 Atypical Fibroxanthoma of the Scalp With Cutaneous Metastasis.
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Atypical fibroxanthoma (AFX) is a dermal spindle-cell sarcoma that is considered a superficial and clinically benign presentation of pleomorphic dermal sarcoma, malignant fibrous histiocytoma, and undifferentiated pleomorphic sarcoma. AFX appears clinically as a discrete red or pink nodule or papule …. Atypical fibroxanthoma (AFX) is a dermal

Arch Dermatol. 2010;146(12):1399–404. PubMed CrossRef Google Scholar Atypical fibroxanthoma is a malignant skin tumor with histologic features similar to those of undifferentiated pleomorphic sarcoma, but lacking its more aggressive behavior. The tumor is composed of pleomorphic cells with hyperchromatic nuclei and abundant cytoplasm, commonly arranged in a spindle cell pattern.


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BACKGROUND: Atypical fibroxanthoma (AFX) is a low-grade sarcoma usually occurring on sun-damaged skin of the head and neck in elderly patients. Metastatic disease has been reported very rarely. The potential aggressiveness of AFX is controversial. OBSERVATIONS: We describe herein a patient who developed metastatic disease in cervical lymph nodes.

Atypical fibroxanthoma (AFX) is a dermal spindle-cell sarcoma that is considered a superficial and clinically benign presentation of pleomorphic dermal sarcoma, malignant fibrous histiocytoma, and undifferentiated pleomorphic sarcoma. Cutaneous atypical fibroxanthoma (AFX) occurs in elderly persons as a small nodule or ulceronodule in actinically damaged skin of the head and neck area. The vast majority of AFX behave in a benign manner, and metastasis is rare. Eight examples of metastasizing AFX are reported. Factors that portend agressive behavior and metastasis are vascular invasion, recurrence, deep tissue invasion Atypical fibroxanthoma of the skin is a low-grade malignancy related to malignant fibrous histiocytoma, which it resembles histologically.: 613 Atypical fibroxanthoma (AFX) A systematic retrospective review of the literature focusing on treatment modality found a recurrence and metastasis rate of 8.0% (5.6% when adjusted for incomplete excisions) and 0.5% for local excision and 4.6% and 3.2% for Mohs micrographic surgery, respectively. DOI: 10.1097/00006534-200304150-00032 Corpus ID: 26453610.